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What is NAD+ (Nicotinamide Adenine Dinucleotide)?

ACTIVE INGREDIENT LIBRARY

NAD+ (nicotinamide adenine dinucleotide) is a vital coenzyme present in all living cells. It acts as a central carrier molecule in cellular metabolism, the energy cycle and enzymatic reactions.

Formed by two nucleotides joined through a pyrophosphate bridge, this dinucleotide structure (C21H27N7O14P2) is one of the most intensively studied molecules in longevity science.

In the scientific literature, NAD+ is a focus of cellular-aging and metabolism research. Studies have explored how cellular NAD+ levels decline with age and have investigated precursors such as NMN and NR for their potential to support NAD+ availability. Research also examines its role in mitochondrial function, DNA-repair enzymes (PARPs) and the sirtuin pathway. These are active scientific research areas rather than established medical treatments.

NATURAL SOURCES
Yeast, milk, fish, mushrooms, whole grains (via the precursor vitamin B3)
SCIENTIFIC LITERATURE
Covarrubias AJ et al. Nat Rev Mol Cell Biol. 2021.
Data source: PubChem · CID 5892
Data source: PubChem · CID 5892

HEALTH REGULATION NOTICE

In accordance with food and cosmetics regulations, the information on this page is for general informational purposes only; active ingredients do not claim to prevent, treat, or cure any disease.

Frequently Asked Questions

NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme found in all living cells. It plays a crucial role as a carrier molecule in cellular metabolism, the energy cycle, and various enzymatic reactions. Its structure consists of two nucleotides linked by a pyrophosphate bridge.

NAD+ is found naturally in foods such as yeast, milk, fish, mushrooms, and whole grains. These sources provide the precursor vitamin B3, which the body can use to synthesize NAD+.

The chemical formula for NAD+ (nicotinamide adenine dinucleotide) is C21H27N7O14P2.

NAD+ is a major focus in the scientific literature, particularly in research areas related to cellular aging and metabolism. Studies have examined the decline in cellular NAD+ levels with age, investigated precursors such as NMN and NR to support NAD+ availability, and explored its role in mitochondrial function, DNA-repair enzymes (PARPs), and the sirtuin pathway. These are active areas of scientific research.

NAD+ is a naturally occurring compound and a vital coenzyme in the body. It is not classified as a drug or medicine. Supplements containing NAD+ or its precursors are not intended to replace medical treatment or a balanced diet. If you have any health conditions, it is essential to consult your doctor.

Although NAD+ is a naturally occurring substance, it is always advisable to consult a healthcare professional before starting any new supplement regimen, especially if you are pregnant, breastfeeding, have a pre-existing medical condition, or are taking other medications. They can provide personalized advice based on your health status.