What is NADH?

NADH is the reduced (hydrogenated) form of nicotinamide adenine dinucleotide. It plays a critical role in energy metabolism within cells. Its primary function is to contribute to the production of ATP (energy) by participating in redox reactions. Chemically, it consists of an adenosine and a nicotinamide group.

NADH is a molecule found in both animal and plant sources in nature. It is naturally synthesized within our cells and plays a role in energy metabolism.

In the scientific literature, NADH has been extensively studied for its role in cellular energy production, mitochondrial functions, and various metabolic pathways. Its central role in energy metabolism has made it an important molecule in many areas of biochemical and physiological research.

No, NADH is not a drug. It is a coenzyme that occurs naturally in our bodies and plays a role in energy metabolism. It is available in the form of dietary supplements, but these supplements are not a substitute for medication and should not be used to treat diseases.

Since NADH occurs naturally in the body, it is generally safe for most people to use. However, as with any dietary supplement, it is recommended that individuals—especially those with chronic conditions, pregnant women, breastfeeding mothers, or those taking regular medication—consult a healthcare professional before use. A healthcare professional will assess its suitability and the proper method of use based on the individual’s specific circumstances.

NADH is considered a nutrient and a dietary supplement ingredient. In the United States, the Food and Drug Administration (FDA) does not approve dietary supplements in the same way it approves drugs before they are marketed. The FDA regulates manufacturers regarding the safety and labeling of dietary supplements. Therefore, rather than requiring “FDA approval,” it is essential that NADH supplements be manufactured and marketed in compliance with relevant regulations.